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    <title>CF Bites Blog</title>
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    <description>Stories, CF research updates, and community news from CF Bites Foundation in Charleston, SC.</description>
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      <title><![CDATA[The Modulator Era: Where CF Treatment Stands Now]]></title>
      <link>https://charlestoncfbites.com/cf-bites-blog/the-modulator-era-where-cf-treatment-stands-now</link>
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      <description><![CDATA[CFTR modulator therapy reshaped cystic fibrosis care for tens of thousands of patients. Here's where treatment stands in 2026, and who still isn't covered.]]></description>
      <pubDate>Thu, 27 Aug 2026 00:00:00 GMT</pubDate>
      <category>Treatment</category>
      <author>EB</author>
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    <item>
      <title><![CDATA[Is There a Cure for Cystic Fibrosis Yet? Where Things Really Stand in 2026]]></title>
      <link>https://charlestoncfbites.com/cf-bites-blog/is-there-a-cure-for-cystic-fibrosis-yet-where-things-really-stand-in-2026</link>
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      <description><![CDATA[The honest answer to the question every CF family gets asked. A plain-English look at CFTR modulators, gene therapy, and how close science actually is to a cure for cystic fibrosis in 2026.
]]></description>
      <pubDate>Fri, 24 Jul 2026 00:00:00 GMT</pubDate>
      <category>Research</category>
      <author>Nicole Gordon</author>
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    <item>
      <title><![CDATA[ALYFTREK Is Here - And It Changes Everything for 95% of CF Patients]]></title>
      <link>https://charlestoncfbites.com/cf-bites-blog/alyftrek-approval-cftr-modulator-2026</link>
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      <description><![CDATA[The FDA has approved expanded use of ALYFTREK and Trikafta, making CFTR modulator therapy available to approximately 95% of all people with cystic fibrosis in the United States. Here's what it means.]]></description>
      <pubDate>Sat, 25 Apr 2026 04:00:00 GMT</pubDate>
      <category>Treatment</category>
      <author>Nicole Gordon</author>
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      <title><![CDATA[Yale Researchers May Have Found a Cure for CF - Before a Baby Is Even Born]]></title>
      <link>https://charlestoncfbites.com/cf-bites-blog/yale-in-utero-gene-editing-cf-cure</link>
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      <description><![CDATA[In a landmark June 2025 study published in PNAS, Yale researchers used gene-editing nanoparticles to correct the CFTR mutation in mice before birth - durably, across multiple organs, into adulthood. The implications for human CF treatment are profound.]]></description>
      <pubDate>Wed, 22 Apr 2026 04:00:00 GMT</pubDate>
      <category>Research</category>
      <author>Nicole Gordon</author>
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      <title><![CDATA[The 10% Problem: mRNA Therapy Targets the CF Patients Trikafta Can't Reach]]></title>
      <link>https://charlestoncfbites.com/cf-bites-blog/mrna-therapy-cf-trikafta-cant-help</link>
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      <description><![CDATA[Approximately 10% of people with cystic fibrosis have mutations where Trikafta doesn't work. mRNA therapy - the same technology behind COVID-19 vaccines - may be their best hope. Here's where the research stands.]]></description>
      <pubDate>Mon, 20 Apr 2026 04:00:00 GMT</pubDate>
      <category>Research</category>
      <author>Nicole Gordon</author>
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    <item>
      <title><![CDATA[Gene Therapy Breakthrough: 88% Chloride Function Restored for CF's Rarest, Hardest-to-Treat Mutations]]></title>
      <link>https://charlestoncfbites.com/cf-bites-blog/gene-therapy-rare-cf-mutations-nanoparticle</link>
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      <description><![CDATA[A new nanoparticle-based CRISPR approach has restored 88–100% of chloride channel function in lab cells carrying the G542X mutation - one of the most severe CF mutations affecting patients current drugs can't reach.]]></description>
      <pubDate>Wed, 15 Apr 2026 04:00:00 GMT</pubDate>
      <category>Research</category>
      <author>Nicole Gordon</author>
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    <item>
      <title><![CDATA[Scientists Break Antibiotic Resistance in CF Lung Bacteria - A Major Step for Lung Disease]]></title>
      <link>https://charlestoncfbites.com/cf-bites-blog/antibiotic-resistance-cf-lung-bacteria-breakthrough</link>
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      <description><![CDATA[A study published in April 2026 discovered how to disable both individual antibiotic resistance and cross-protection between bacteria in CF patients' lungs, making previously untreatable infections vulnerable again.]]></description>
      <pubDate>Fri, 10 Apr 2026 04:00:00 GMT</pubDate>
      <category>Research</category>
      <author>Nicole Gordon</author>
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    <item>
      <title><![CDATA[From 2 Years to 61: How CF Life Expectancy Was Transformed - and Why the Fight Isn't Over]]></title>
      <link>https://charlestoncfbites.com/cf-bites-blog/cf-life-expectancy-from-two-years-to-sixty-one</link>
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      <description><![CDATA[In the 1960s, a CF diagnosis meant a child was unlikely to reach school age. Today, the projected median survival is 61 years. This is the story of how science, community, and relentless fundraising rewrote the future of cystic fibrosis.]]></description>
      <pubDate>Sun, 05 Apr 2026 04:00:00 GMT</pubDate>
      <category>Community</category>
      <author>Nicole Gordon</author>
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